Lots of things cause aneuploidy but does that mean they cause cancer? Could it be that it's actually protective?
Nat Rev Mol Cell Biol. 2009 Jul;10(7):478-87. Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis
Now I must explain the Subtle Approach. There are three occasions on which we cannot use the Direct Opening, and these we must consider carefully: (1) when our cause is discreditable, that is, when the subject itself alienates the hearer from us; (2) when the hearer has apparently been won over by the previous speakers of the opposition; (3) or when the hearer has become wearied by listening to the previous speakers.
- Cicero "Ad Herennium"
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