O-toluidine and Aniline Again Associated with Bladder Cancer
A recently published study in Occupational and Environmental Medicine reanalyzed the results of a 1991 investigation conducted by NIOSH of 1749 workers potentially exposed to o-toluidine and aniline at a chemical manufacturing plant and the incidence of bladder cancer. In the reanalysis, the investigators used updated exposure categories based on additional information ascertained through plant visits, employee interviews, documents, and answers provided by company and union officials on specific questions. Increased risks of bladder cancer were observed the longer the exposed employee worked at the facility and the longer the latency period from the date the employee initially worked in a department in which exposure occurred.
The investigators concluded that the findings were comparable to the results reported in 1991 by NIOSH that workers at the plant have an increased risk of bladder cancer.
