While some fret that man-made nanoparticles may bear unanticipated hazards that won't manifest for decades cancer researchers press forward with the development of revolutionary nano-scale drugs. What are they? How will they work? Will they be regulated as drugs, devices or biologics? An excellent (and free) discussion can be found at Nature Reviews: Clinical Oncology in "Conscripts of the Infinite Armada: Systemic Cancer Therapy Using Nanomaterials".
Now I must explain the Subtle Approach. There are three occasions on which we cannot use the Direct Opening, and these we must consider carefully: (1) when our cause is discreditable, that is, when the subject itself alienates the hearer from us; (2) when the hearer has apparently been won over by the previous speakers of the opposition; (3) or when the hearer has become wearied by listening to the previous speakers.
- Cicero "Ad Herennium"
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