Let's Hope Not

Posted on July 12, 2010 by David Oliver
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"'What we have heard back from drug companies is that, if it has the word 'PPAR' in it, it's dead,” says Bruce Spiegelman, a cell biologist at the Dana-Farber Cancer Institute." That's from "Diabetes Drug Woes Spell Trouble for the Entire Drug Family." The most famous PPAR-gamma drug out there is, of course, Avandia.

Why hope PPAR-gamma drugs aren't dead? Well, read "in Vitro and In Vivo Therapeutic Efficacy of the PPAR-gamma Agonist Troglitazone in Combination With Cisplatin Against Malignant Pleural Mesothelioma Cell Growth". The PPAR-gamma agonist not only inhibited malignant pleural mesothelioma cell growth it also lengthened survival.

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