Sanded Joint Compound With Chrysotile Doesn't Migrate to the Pleura Nor Does it Produce Inflammation
Six hours a day, for five days, rats were exposed either to amosite or to joint compound with chrysotile. Over the course of a year subsets were sacrificed and their lungs examined. The rats exposed to amosite sustained an inflammatory response and by the end of four weeks had developed evidence of interstitial fibrosis and inflammation in the parietal pleura. Those rats exposed to chrysotile-containing joint compound never showed evidence of fibrosis and their bodies cleared the chrysotile fibers quickly. By the end of the year there was still no evidence of inflammation or migration.
